Please choose any Florence, South Carolina hotel below to view the hotel description, room rates and information.

The Florence Hotel Guide is your personal Internet resource for discount hotels, motels, inns and lodging in Florence, South Carolina. We feature hotels, motels and resorts in all price ranges from five star hotels to inexpensive inns and motels with many special web discounts in Florence, South Carolina and the surrounding area. The Florence area is a great place to stay, conduct business, vacation or play.

SanPedro.com is a great resource for Florence, South Carolina hotels and much more! If you're looking for information about Florence travel you've come to the right place.




All Countries  :  United States  :  South Carolina  :  Florence

Florence, SC Hotels

Holiday Inn Express Hotel & Suites FLORENCE I-95 & I-20 CIVIC CTR

Holiday Inn Express Hotel & Suites FLORENCE I-95 & I-20 CIVIC CTR
3440 WEST RADIO DRIVE
Florence, SC 29501
Nightly Rates: ( 124.00 - 154.00 )
2 Star
Experience Top-Rated Service at Our Florence, SC Hotel Centrally located between Florida and New York in the heart of Florence, South Carolina, this hotel is at the intersection of I-95 and I-20 near ...see more


Comfort Suites Florence

Comfort Suites Florence
2120 West Lucas Street
Florence, SC 29501
Nightly Rates: ( 139.99 - 139.99 )
2 Star
Speed on in to the new Comfort Suites of Florence. We are walking distance to several restaurants and lounges, a short drive to golf, museums, shopping, concerts, and the Darlington Motor Speedway. Ou...see more


Best Western Inn

Best Western Inn
1808 W Lucas Street
Florence, SC 29501
Nightly Rates: ( 84.00 - 86.25 )
2 Star
Stay at this pet-friendly Florence, South Carolina hotel located close to the Florence Civic Center, the Darlington Raceway and the Florence Regional Airport. Welcome to the BEST WESTERN Inn, locate...see more


Holiday Inn Hotel & Suites FLORENCE SC @ I-95 & US HWY 52

Holiday Inn Hotel & Suites FLORENCE SC @ I-95 & US HWY 52
1819 LUCAS ST
Florence, SC 29501
Nightly Rates: ( 64.00 - 80.00 )
2 Star
Enjoy a taste of 'Southern Hospitality® at Holiday Inn Hotel&Suites in Florence,SC. We are conveniently located off I-95, exit 164. Only minutes from:Florence Airport, Amtrak, Powers Aviation, Civi...see more


Wingate by Wyndham Florence

Wingate by Wyndham Florence
2123 W. Lucas Street
Florence, SC 29501
Nightly Rates: ( 89.00 - 99.00 )
2 Star
Our convenient airport location, just 10 minutes away, and proximity to shopping, dining and entertainment makes us the hotel of choice among serious business travelers. At Wingate by Wyndham Florenc...see more


Sleep Inn Florence

Sleep Inn Florence
1833 Florence Park Dr. I-95 & US 52
Florence, SC 29502
Nightly Rates: ( 69.97 - 69.97 )
2 Star
Inside corridor rooms. Restaurants within walking distance. In-room safe warranty fee: 1.50 per night. City - I-95 at ex. 164...see more


SpringHill Suites Florence

SpringHill Suites Florence
2670 Hospitality Boulevard
Florence, SC 29501
Nightly Rates: ( 119.00 - 129.00 )
2 Star
Welcome to SpringHill Suites in Florence, SC - a hotel that offers space and style at affordable prices. Our rooms offer suites that are 25% larger than comparably priced hotel rooms in our market; t...see more


Holiday Inn Express Hotel & Suites Florence I-95 @ Hwy 327

Holiday Inn Express Hotel & Suites Florence I-95 @ Hwy 327
2101 FLORENCE HARLLEE BLVD,I-95, EXIT 170@HWY 327-WILLISTON RD
Florence, SC 29506
Nightly Rates: ( 92.00 - 116.00 )
2 Star
Welcome to the Holiday Inn Express Florence Hotel This premiere Holiday Inn Express hotel is conveniently situated on Hwy 327 and I-95 in Florence, SC. Our hotel's location in the suburbs takes you ...see more


Econo Lodge Florence

Econo Lodge Florence
1920 West Lucas Street
Florence, SC 29501
Nightly Rates: ( 46.83 - 56.20 )
2 Star
The Econo Lodge is the perfect value when your travel plans call for Florencee, SC. Each guestroom in features free high speed internet, iron and ironing boards, hairdryers, coffe makers with free co...see more


Americas Best Value Inn Florence

Americas Best Value Inn Florence
3024 TV Road
Florence, SC 29501
Nightly Rates: ( 45.00 - 45.00 )
1 Star
The Americas Best Value Inn of Florence is located just off of Interstate 95 at exit 169/TV road. Our 2-story, exterior design inn offers 96 nicely furnished guest rooms featuring free wireless high-s...see more


Quality Inn & Suites Civic Center

Quality Inn & Suites Civic Center
150 Dunbarton Drive
Florence, SC 29501
Nightly Rates: ( 89.99 - 125.00 )
2 Star
The Quality Inn is located 10 miles to Darlington Raceway, 8 miles to the airport and walking distance to Magional Mall, Civic Center, Outback Steak House, Olive Garden, and Chuck E Cheese. The Freedo...see more


Courtyard Florence

Courtyard Florence
2680 Hospitality Blvd.
Florence, SC 29501
Nightly Rates: ( 119.00 - 119.00 )
3 Star
It's a new stay at the Courtyard by Marriott in Florence, South Carolina. This Florence, SC hotel features a brand new state-of-the-art lobby with inviting, flexible spaces to work or relax in, free W...see more


Howard Johnson Express Inn and Suites Florence SC

Howard Johnson Express Inn and Suites Florence SC
3821 Bancroft Road
Florence, SC 29501
Nightly Rates: ( 62.95 - 65.95 )
1 Star
An Award Winning, AAA approved property, conveniently located off I-95, Exit 157, just 3 miles south of intersection of I-20/I-95. This is a perfect stopping point between Florida and New York, clos...see more


Baymont Inn & Suites Florence

Baymont Inn & Suites Florence
1826 West Lucas Street
Florence, SC 29501
Nightly Rates: ( 51.75 - 59.25 )
2 Star
The Baymont Inn and Suites of Florence, SC is located at I-95 Exit 164 US 52 and is an excellent halfway point for those I-95 travelers heading north or south. The Baymont Inn and Suites of Florence,...see more


Super 8 Florence

Super 8 Florence
1832 1/2 Lucas Street
Florence, SC 29501
Nightly Rates: ( 56.95 - 66.95 )
1 Star
Welcome to the Super 8 Florence, SC Easy Access from I-95 Property is Conveniently Located near Shopping, Restaurants, Entertainment and Local Attractions Property has Clean, Comfortable Rooms and Fri...see more


Microtel Inn and Suites Florence

Microtel Inn and Suites Florence
1912 Enterprise Drive
Florence, SC 29502
Nightly Rates: ( 47.10 - 58.72 )
1 Star
Microtel Inn and Suites Florence, SC - Enjoy a Quality Hotel Room at a Discount Hotel Price. Enjoy consistency, quality, reasonable prices and great service each time you stay with Microtel Inns and ...see more


Residence Inn Florence

Residence Inn Florence
2660 Hospitality Boulevard
Florence, SC 29501
Nightly Rates: ( 129.00 - 139.00 )
3 Star
The Residence Inn by Marriott is the newest extended stay hotel in Florence, SC. Guests of the Residence Inn will enjoy larger suites (50% larger than a standard hotel room), flat panel LCD TVs with 4...see more


Ramada Florence Center

Ramada Florence Center
1819 West Lucas Street
Florence, SC 29501
Nightly Rates: ( 62.10 - 69.00 )
1 Star
Welcome to the Ramada Florence Center, the preferred choice among full service hotels for business, leisure, and convention guests in Florence, South Carolina. This Florence hotel is just minutes to ...see more


Ramada Florence SC

Ramada Florence SC
3311 Meadors Road
Florence, SC 29502
Nightly Rates: ( 59.00 - 69.00 )
2 Star
The Ramada at Young's Plantation of Florence, South Carolina is conveniently located at Exit 157 US 76. The property is a great halfway point on I-95 for travelers heading north or south. The Ramada a...see more


Red Roof Inn Florence Civic Center

Red Roof Inn Florence Civic Center
2690 David McLeod Blvd
Florence, SC 29501
Nightly Rates: ( 51.24 - 56.24 )
2 Star
Magnolia Mall, with 70 great stores, is right across the street! We re adjacent to the Florence City-County Civic Center; Darlington International Raceway is just 12 miles and North Carolina Speedway ...see more


Suburban Extended Stay Hotel

Suburban Extended Stay Hotel
1914 West Lucas Street I-95 & US 52
Florence, SC 29501
Nightly Rates: ( 42.95 - 64.95 )
1 Star
When you stay at a Suburban Extended Stay Hotel, you can rest assured that you're getting a good deal. You will have your own in-room kitchen, on site laundry, FREE cable TV, and Internet/data connect...see more


Days Inn Florence/I-95 South

Days Inn Florence/I-95 South
3783 West Palmetto Street
Florence, SC 29501
Nightly Rates: ( 49.00 - 59.00 )
1 Star
Golf Packages Available AARP/AAA 20 percent Discount off rack rate 4 Sunburst Rating Shopping nearby Magnolia Mall 3 mi Florence Mall 4 mi. Additional restaurants nearby McLeod Regional Medical Cente...see more


Fairfield Inn Florence

Fairfield Inn Florence
140 Dunbarton Drive
Florence, SC 29501
Nightly Rates: ( 64.00 - 84.00 )
2 Star
Enjoy our Southern Hospitality at the beautiful Fairfield Inn in Florence, SC. We are minutes away from Darlington NASCAR Raceway and the Florence Civic Center. Enjoy a day of shopping at Magnolia Mal...see more


Howard Johnson Inn Florence

Howard Johnson Inn Florence
2038 W Lucas Street
Florence, SC 29501
Nightly Rates: ( 49.95 - 49.95 )
1 Star
The Howard Johnson Inn Florence - North is a great place to stay while you are in the Florence area. We are conveniently located on Interstate 95, just north of the Interstate 20 junction and halfway...see more


Country Inn & Suites By Carlson Florence

Country Inn & Suites By Carlson Florence
1739 MANDEVILLE ROAD
Florence, SC 29501
Nightly Rates: ( 78.30 - 107.00 )
2 Star
Hotel features complimentary continental breakfast, complimentary local calls. Spacious guest rooms feature desk, coffeemaker, iron/board, hairdryer, cable TV with HBO, AM/FM alarm clock radio, wirele...see more


Travelodge Florence

Travelodge Florence
3783A W. Palmetto St.
Florence, SC 29502
Nightly Rates: ( 101.25 - 135.00 )
1 Star
An excellent stopping point between Florida and New York, our hotel is conveniently located on I-95 exit 157, just 6 miles South of the I-20 Intersection. Popular area attractions including Darli...see more


Country Hearth Inn Florence

Country Hearth Inn Florence
831 South Irby Street
Florence, SC 29501
Nightly Rates: ( 47.70 - 53.00 )
3 Star
Cozy Lobby With Fireplace And Small Reading Library. 102 Rooms With King Or Double Beds. Four -4- Jr. Suites With Couch, Refrigerators Microwave, Hairdryers. Located Just South Of Downtown Florence. N...see more


Affordable Suites Florence

Affordable Suites Florence
530 Woody Jones Blvd
Florence, SC 29501
Nightly Rates: ( 59.00 - 69.00 )
Affordable Suites are developed to be an economic solution to temporary housing without the hassle of contractual lease obligations, with added living space that makes staying longer much more comfort...see more


Check Rates and Availability

Arrival Date

Departure Date
Adults
Children