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3253 WILLIAM ST.
Cape Girardeau, MO 63701
Nightly Rates: ( 113.96 - 113.96 )
2 Star
Welcome to Our Cape Girardeau Hotel Just off Interstate 55 at exit 96, the Holiday Inn Express Hotel & Suites Cape Girardeau I-55 offers hotel guests 102 spacious, contemporary suites. Vacation and business guests alike choose these accommodations for a comfortable and convenient stay. Our Cape Girardeau, Missouri hotel is just minutes from Southeast Missouri State University, where guests are encouraged to cheer on the Redhawks in football and basketball. We're also only 10 miles from Trail of Tears State Park, so families can enjoy picnics, hiking, biking and fishing. Be sure to stop by the Bushyhead Memorial, as well, which commemorates those whose lives were lost on this trail in 1838. Business travelers appreciate our Cape Girardeau, Missouri hotel's convenient location close to St. Francis Hospital, Southeast Missouri Hospital, Doctors Park, the Show Me Center, Procter & Gamble, Nordenia, Shawnee Park and Biokyowa. We provide two spacious meeting rooms, as well, which feature A/V equipment ideal for business functions or special events. With the help of our professional staff, your event can be a success. At our Girardeau hotel, we know it's the extra perks that make your stay unforgettable. We provide an indoor pool and well-equipped fitness center to help you relax and unwind. Be sure to stop by our breakfast bar each morning, too, for biscuits, eggs, fruit and our signature cinnamon rolls. We look forward to your next visit!
Welcome to the Holiday Inn Express Hotel & Suites

· American Dollars is the native currency.
· Check in time is 3:00 PM
· Check out time is 11:00 AM
· Time Zone is GMT
· Opened in 2005
· 102 rooms.
· 0 suites.
· 4 floors.
I-55 north 6 miles to exit #96, hotel on the right at William Street & I-55.
I-70 east towards St. Louis and merge to I-55 South in Downtown. Follow I-55 115 miles south to exit #96 and turn left on William Street. Hotel on right side.
Rural - RURAL
Cape Girardeau Regional Airport, (CGI), 6.00, N, Mile; Lambert International Airport, (STL), 129.00, S, Mile; Memphis International Airport, (MEM), 147.00, S, Mile
For those persons savorying seafood, this is the place. Just a few yards from the entrance to the hotel, convenient and easy to walk to.
Cracker BarrelEnjoy the well renowned service and food that so many people like. Located on the same complex as the hotel, just a short walk around the corner
Texas RoadhouseGet a little taste of Texas with their signature hand cut steaks, fall off the bone ribs, ice cold beer and much more. Located within a short walk of the hotel on the same complex.
Olive GardenEnjoy a taste of Italian at this restaurant. Located just a hop, skip and jump from the front of the hotel entrance.
Panera BreadFeaturing fresh baked breads, delicious sandwiches, soups and pastries. Located on the North East corner of the complex from the hotel.
Honey Baked Ham CafeThis Cafe is packed full with a variety of deli sandwiches featuring the famous honey baked ham.
